MapQuest Driving Directions San Francisco, CA to Saint Louis, MO

San Francisco, CA

Saint Louis, MO

Route 1

Go east on I-80 E.
2063.9851 miles
31hr 54min
  1. Start out going east on McAllister St toward Carlton B Goodlett Pl.

    Then 0.27 miles
  2. Take the 3rd right onto Hyde St.

    1. Hyde St is just past Breen Pl

    2. If you reach Leavenworth St you've gone a little too far

    Then 0.14 miles
  3. Hyde St becomes 8th St.

    Then 0.60 miles
  4. Turn left onto Bryant St.

    1. Bryant St is 0.1 miles past Harrison St

    2. Smart Center San Francisco is on the corner

    3. If you reach Brannan St you've gone about 0.1 miles too far

    Then 0.00 miles
  5. Merge onto I-80 E via the ramp on the left toward Oakland.

    Then 6.40 miles
  6. Keep left to take I-80 E toward Berkeley/Sacramento/I-580 W/San Rafael.

    Then 5.27 miles
  7. Keep left to take I-80 E toward Vallejo/Sacramento (Portions toll).

    Then 69.23 miles
  8. Keep right to take I-80 E via EXIT 82 toward Reno (Passing through Nevada, then crossing into Utah).

    Then 655.01 miles
  9. Merge onto I-80 E via EXIT 304 toward Cheyenne.

    Then 5.12 miles
  10. Keep left to take I-80 E toward Cheyenne (Passing through Wyoming, then crossing into Nebraska).

    Then 868.87 miles
  11. Take the US-6/WEST O ST exit, EXIT 396, toward Downtown.

    Then 0.25 miles
  12. Turn left onto W O St/US-6 E/NE-2. Continue to follow W O St.

    Then 44.18 miles
  13. W O St becomes US-34 E.

    Then 0.65 miles
  14. Turn right onto US-75 S/S Highway 75. Continue to follow US-75 S.

    1. US-75 S is 0.3 miles past 4th St

    Then 12.73 miles
  15. US-75 S becomes NE-2 (Crossing into Iowa).

    Then 2.05 miles
  16. NE-2 becomes IA-2.

    Then 3.07 miles
  17. Merge onto I-29 S toward Kansas City (Crossing into Missouri).

    1. If you reach 225th Ave you've gone about 1.1 miles too far

    Then 119.71 miles
  18. Merge onto I-435 E via EXIT 14 toward St Louis.

    Then 28.39 miles
  19. Merge onto I-70 E via EXIT 63B on the left toward St Louis.

    Then 201.92 miles
  20. Merge onto I-64 E/US-40 E via EXIT 210A toward Chesterfield.

    Then 39.46 miles
  21. Take the 14th St exit, EXIT 39A.

    Then 0.20 miles
  22. Turn left onto S 14th St.

    Then 0.48 miles
  23. Welcome to SAINT LOUIS, MO.

    1. Your destination is just past Pine St

    2. If you reach Locust St you've gone a little too far

    Then 0.00 miles