MapQuest Driving Directions Des Moines, IA to Oklahoma City, OK

Des Moines, IA

Oklahoma City, OK

Route 1

Go west on I-235 W.
544.6021 miles
8hr 15min
  1. Start out going north on 2nd Ave toward Watson Powell Jr Way.

    Then 0.46 miles
  2. Merge onto I-235 W via the ramp on the left.

    Then 8.27 miles
  3. Merge onto I-35 S via EXIT 123A toward Kansas City (Crossing into Missouri).

    Then 178.70 miles
  4. Merge onto I-29 N/US-71 N via EXIT 8B toward KCI Airport.

    Then 3.45 miles
  5. Merge onto I-635 S via EXIT 3B on the left toward Kansas.

    Then 2.14 miles
  6. Keep right to take I-635 S (Crossing into Kansas).

    Then 5.60 miles
  7. Merge onto I-70 W/Kansas Tpke W via EXIT 4B toward Topeka (Portions toll).

    Then 51.19 miles
  8. Keep left to take I-470 W/Kansas Tpke W toward I-335 S/South Topeka/Wichita (Portions toll).

    Then 6.67 miles
  9. Take I-335 S/Kansas Tpke S toward Wichita (Portions toll).

    Then 50.60 miles
  10. I-335 S/Kansas Tpke S becomes I-35 S (Portions toll) (Crossing into Oklahoma).

    Then 228.94 miles
  11. Keep right to take I-44 W/OK-66 W/Historic Route 66 W/Northeast Expy W via EXIT 133 toward Lawton/Amarillo.

    Then 3.19 miles
  12. Merge onto I-235 S/US-77 S via EXIT 127 toward Downtown/Okla City.

    Then 4.17 miles
  13. Take the N 6th St exit, EXIT 1F, toward Walnut St/Downtown.

    Then 0.24 miles
  14. Turn right onto Harrison Ave.

    1. If you are on N Walnut Ave and reach NE 5th St you've gone a little too far

    Then 0.21 miles
  15. Turn slight right onto NE 4th St.

    1. NE 4th St is 0.1 miles past N Oklahoma Ave

    2. Leos Bar-B-Q is on the right

    Then 0.53 miles
  16. Turn left onto N Walker Ave.

    1. N Walker Ave is 0.1 miles past N Hudson Ave

    2. If you reach N Dewey Ave you've gone a little too far

    Then 0.25 miles
  17. Welcome to OKLAHOMA CITY, OK.

    1. Your destination is just past Couch Dr

    2. If you reach W Main St you've gone a little too far

    Then 0.00 miles