MapQuest Driving Directions Chicago, IL to Winston Salem, NC

Chicago, IL

Winston Salem, NC

Route 1

Go east on I-90 E/I-94 E.
709.158 miles
11hr 29min
  1. Start out going north on N Lasalle St toward W Randolph St.

    Then 0.09 miles
  2. Take the 1st left onto W Randolph St.

    1. If you reach W Lake St you've gone a little too far

    Then 0.39 miles
  3. Keep right at the fork to continue on W Randolph St.

    Then 0.31 miles
  4. Merge onto I-90 E/I-94 E via the ramp on the left.

    1. If you reach N Halsted St you've gone a little too far

    Then 3.01 miles
  5. Keep left to take I-90 (EXPRESS) E/I-94 E/Dan Ryan Expy S.

    Then 3.93 miles
  6. Take the I-90 E exit, EXIT 59A, toward Skyway/Indiana Toll Rd.

    Then 0.28 miles
  7. Merge onto I-90 (LOCAL) E/I-94 E/Dan Ryan Expy S.

    Then 0.61 miles
  8. Merge onto I-90 E via EXIT 59A on the left toward Indiana Toll Rd (Portions toll) (Crossing into Indiana).

    Then 24.04 miles
  9. Merge onto I-65 S via EXIT 17 toward Indianapolis.

    Then 133.59 miles
  10. Keep left to take I-65 S toward I-465 S.

    Then 16.81 miles
  11. Merge onto I-70 E via EXIT 112A on the left toward Columbus OH (Crossing into Ohio).

    Then 106.70 miles
  12. Merge onto I-75 S via EXIT 33A toward Dayton.

    Then 8.82 miles
  13. Merge onto US-35 E via EXIT 52B toward Xenia/OH-4.

    Then 80.04 miles
  14. Keep left to take US-35 E toward Jackson/Athens (Crossing into West Virginia).

    Then 95.12 miles
  15. Merge onto I-64 E toward St Albans/Charleston (Portions toll).

    Then 78.70 miles
  16. Keep right to take I-77 S toward Bluefield (Portions toll) (Crossing into Virginia).

    Then 75.51 miles
  17. Merge onto I-77 S via EXIT 81 toward Charlotte NC (Crossing into North Carolina).

    Then 37.13 miles
  18. Merge onto I-74 E via EXIT 101 on the left toward Mount Airy/Winston-Salem.

    Then 12.40 miles
  19. Merge onto US-52 S via the exit on the left toward Winston/Salem.

    Then 30.87 miles
  20. Merge onto I-40 Bus W/US-421 N/US-158 W/NC-150 W via EXIT 109B toward NC-150 W/Downtown.

    Then 0.42 miles
  21. Take the Main Street exit, EXIT 5D, toward Downtown/First St.

    Then 0.22 miles
  22. Turn right onto S Main St.

    1. Salem Funeral & Cremation Services, LLC is on the corner

    Then 0.17 miles
  23. Welcome to WINSTON SALEM, NC.

    1. Your destination is 0.1 miles past E 1st St

    2. If you reach E 3rd St you've gone about 0.1 miles too far

    Then 0.00 miles