MapQuest Driving Directions Louisville, KY to Birmingham, AL

Louisville, KY

Birmingham, AL

Route 1

Go south on I-65 S (Crossing into Tennessee).
365.048 miles
5hr 29min
  1. Start out going south on S 1st St toward Billy Goat Strut Aly.

    Then 0.28 miles
  2. Merge onto I-65 S via the ramp on the left toward Nashville (Crossing into Tennessee).

    Then 175.31 miles
  3. Keep right to take I-65 S via EXIT 210 toward Huntsville (Crossing into Alabama).

    Then 188.19 miles
  4. Merge onto I-20 E/I-59 N via EXIT 261A on the left toward Atlanta/Gadsden.

    Then 1.00 miles
  5. Take the 22nd St exit, EXIT 125B.

    Then 0.22 miles
  6. Turn slight right onto 22nd St N.

    Then 0.06 miles
  7. Welcome to BIRMINGHAM, AL.

    1. If you reach 7th Ct N you've gone a little too far

    Then 0.00 miles