MapQuest Driving Directions Saint Paul, MN to Saint Louis, MO

Saint Paul, MN

Saint Louis, MO

Route 1

Go south on US-52 S.
528.7141 miles
8hr 38min
  1. Start out going east on Kellogg Blvd W toward N Wabasha St.

    Then 0.27 miles
  2. Turn right onto Robert St N.

    1. Robert St N is just past Minnesota St N

    Then 0.61 miles
  3. Turn left onto County Hwy-40/Plato Blvd E.

    1. County Hwy-40 is 0.1 miles past E Fairfield Ave

    2. Backstreet Pizzeria is on the right

    3. If you reach E Wood St you've gone about 0.2 miles too far

    Then 0.33 miles
  4. Turn right onto W Lafayette Frontage Rd.

    1. W Lafayette Frontage Rd is just past State St

    2. If you reach E Lafayette Frontage Rd you've gone a little too far

    Then 0.32 miles
  5. Merge onto US-52 S.

    Then 77.67 miles
  6. Merge onto US-63 S via EXIT 51 toward Rochester/Airport/Stewartville/I-90 W.

    Then 18.94 miles
  7. Turn left onto State Highway 16/US-63 S/MN-16. Continue to follow US-63 S/MN-16.

    Then 5.14 miles
  8. Turn right onto N Section Ave/US-63 S/County Hwy-1. Continue to follow US-63 S (Crossing into Iowa).

    1. Dairy Queen is on the right

    2. If you are on MN-16 and reach Center Ave you've gone a little too far

    Then 86.47 miles
  9. Keep left at the fork to go on W Mullan Ave.

    Then 0.23 miles
  10. Turn slight left onto Washington St.

    1. Washington St is 0.1 miles past US-63 N

    Then 2.95 miles
  11. Merge onto I-380 S/US-20 E/IA-27 S via EXIT 71 toward Cedar Rapids/Dubuque.

    Then 6.55 miles
  12. Merge onto IA-27 S toward Cedar Rapids (Crossing into Missouri).

    Then 154.28 miles
  13. IA-27 S becomes MO-27.

    Then 7.01 miles
  14. Stay straight to go onto US-61 S.

    Then 44.41 miles
  15. Turn slight left onto US-61 S/Highway 61 N. Continue to follow US-61 S.

    1. US-61 S is just past Highway F

    Then 111.44 miles
  16. Stay straight to go onto I-64 E/US-40 E.

    Then 11.44 miles
  17. Take the 14th St exit, EXIT 39A.

    Then 0.20 miles
  18. Turn left onto S 14th St.

    Then 0.48 miles
  19. Welcome to SAINT LOUIS, MO.

    1. Your destination is just past Pine St

    2. If you reach Locust St you've gone a little too far

    Then 0.00 miles