MapQuest Driving Directions Cape Girardeau, MO to Springfield, MO

Cape Girardeau, MO

Springfield, MO

Route 1

268.926 miles
4hr 19min
  1. Start out going south on N Kingshighway St/US-61 S/MO-34 toward Bessie St. Continue to follow N Kingshighway St/US-61 S.

    Then 3.19 miles
  2. Merge onto I-55 S toward Sikeston.

    Then 27.50 miles
  3. Merge onto US-60 W via EXIT 66B toward Dexter/Poplar Bluff.

    Then 51.44 miles
  4. Merge onto US-60 W/US-67 N toward Springfield/St Louis.

    Then 4.56 miles
  5. Merge onto US-60 W toward Van Buren/Springfield.

    Then 172.53 miles
  6. Merge onto US-65 N toward Springfield.

    Then 5.63 miles
  7. Take the US-65 Bus/Chestnut Expwy exit.

    Then 0.24 miles
  8. Keep left to take the ramp toward Ozarks Technical Community College/Drury University/Missouri State University.

    Then 0.02 miles
  9. Turn left onto E Chestnut Expy/US-65 Bus S. Continue to follow E Chestnut Expy.

    Then 3.82 miles
  10. Welcome to SPRINGFIELD, MO.

    1. Your destination is 0.1 miles past N Jefferson Ave

    2. If you are on I-44 Bus Loop W and reach N Campbell Ave you've gone a little too far

    Then 0.00 miles