MapQuest Driving Directions Columbia, MO to Chicago, IL

Columbia, MO

Chicago, IL

Route 1

Go east on I-70 E/US-40 E.
385.104 miles
6hr 23min
  1. Start out going east on E Broadway toward S 9th St.

    Then 0.36 miles
  2. Turn left onto N College Ave/MO-763.

    1. N College Ave is just past Waugh St

    2. If you reach Willis Ave you've gone a little too far

    Then 0.86 miles
  3. Turn right onto Business Loop 70 E/I-70 Loop E.

    1. Arch & Column Pub is on the corner

    Then 1.08 miles
  4. Merge onto I-70 E/US-40 E.

    Then 19.36 miles
  5. Take the US-54 exit, EXIT 148, toward Auxvasse/Mexico/Fulton.

    Then 0.21 miles
  6. Turn left onto US-54 E/US Highway 54. Continue to follow US-54 E.

    Then 18.17 miles
  7. Turn right onto E Liberty St/US-54 E. Continue to follow US-54 E.

    Then 10.37 miles
  8. Turn left onto Highway 54/US-54 E/MO-19. Continue to follow US-54 E/MO-19.

    1. If you are on Highway BB and reach Audrain Road 757 you've gone about 1 mile too far

    Then 8.09 miles
  9. Turn right onto Highway 54/US-54 E. Continue to follow US-54 E (Crossing into Illinois).

    1. US-54 E is 0.9 miles past Audrain Road 456

    Then 55.60 miles
  10. Turn left onto N Jackson St/US-54 E/IL-107. Continue to follow US-54 E/IL-107.

    1. US-54 E is just past Fayette Ct

    2. CASEY'S GENERAL STORE #331 is on the corner

    3. If you reach N Illinois St you've gone a little too far

    Then 5.10 miles
  11. Merge onto I-72 E/US-36 E toward Springfield.

    1. If you are on State Highway 107 and reach 290th Ave you've gone about 0.3 miles too far

    Then 67.47 miles
  12. Stay straight to go onto I-55 N.

    Then 194.27 miles
  13. Merge onto I-90 W/I-94 W via EXIT 292A toward Wisconsin.

    Then 3.33 miles
  14. Take the E Washington Blvd exit, EXIT 51C, toward 100 North.

    Then 0.16 miles
  15. Turn right onto W Washington Blvd.

    Then 0.05 miles
  16. W Washington Blvd becomes W Washington St.

    Then 0.16 miles
  17. Keep left at the fork to continue on W Washington St.

    Then 0.45 miles
  18. Welcome to CHICAGO, IL.

    1. Your destination is just past N Wells St

    2. If you reach N Clark St you've gone a little too far

    Then 0.00 miles