MapQuest Driving Directions Kirksville, MO to Saint Louis, MO

Kirksville, MO

Saint Louis, MO

Route 1

Go south on US-63 S.
212.665 miles
3hr 25min
  1. Start out going south on S Marion St toward E McPherson St.

    Then 0.32 miles
  2. Turn right onto E Normal St.

    Then 0.06 miles
  3. Take the 1st left onto S Franklin St.

    1. If you are on W Normal St and reach S Elson St you've gone a little too far

    Then 1.66 miles
  4. Turn right onto S Baltimore St/US-63 Bus S/MO-11. Continue to follow US-63 Bus S.

    1. US-63 Bus S is 0.1 miles past Shepherd Ave

    Then 2.13 miles
  5. US-63 Bus S becomes US-63 S.

    Then 86.20 miles
  6. Take the MO-PP exit toward I-70/US-40/Kansas City/St Louis.

    Then 0.52 miles
  7. Merge onto Old 63.

    Then 0.42 miles
  8. Merge onto I-70 E/US-40 E via the ramp on the left toward St Louis.

    1. If you reach Conley Rd you've gone about 0.1 miles too far

    Then 81.22 miles
  9. Merge onto I-64 E/US-40 E via EXIT 210A toward Chesterfield.

    Then 39.46 miles
  10. Take the 14th St exit, EXIT 39A.

    Then 0.20 miles
  11. Turn left onto S 14th St.

    Then 0.48 miles
  12. Welcome to SAINT LOUIS, MO.

    1. Your destination is just past Pine St

    2. If you reach Locust St you've gone a little too far

    Then 0.00 miles