MapQuest Driving Directions Saint Louis, MO to Cincinnati, OH

Saint Louis, MO

Cincinnati, OH

Route 1

Go east on I-70 E (Crossing into Illinois).
349.845 miles
5hr 31min
  1. Start out going east on Olive St toward N 13th St.

    Then 0.16 miles
  2. Take the 2nd left onto N Tucker Blvd.

    1. N Tucker Blvd is just past N 13th St

    2. US Post Office is on the right

    3. If you reach N 11th St you've gone a little too far

    Then 0.64 miles
  3. N Tucker Blvd becomes N Tucker Ave.

    Then 0.50 miles
  4. Stay straight to go onto I-70 E (Crossing into Illinois).

    Then 18.95 miles
  5. Merge onto I-70 E via EXIT 20A toward Indianapolis (Crossing into Indiana).

    Then 210.75 miles
  6. Merge onto I-74 E/I-465 S/US-40 E/US-36 E via EXIT 69 toward Cincinnati.

    Then 16.90 miles
  7. Merge onto I-74 E via EXIT 49 toward Cincinnati (Crossing into Ohio).

    Then 87.51 miles
  8. Merge onto US-52 E toward Cincinnati.

    Then 10.83 miles
  9. Stay straight to go onto I-75 S.

    Then 2.75 miles
  10. Take the Seventh St exit, EXIT 1E.

    Then 0.30 miles
  11. Merge onto W 7th St.

    Then 0.51 miles
  12. Turn left onto Vine St.

    1. Vine St is just past Doerr Aly

    2. Knockback Nats is on the left

    3. If you are on E 7th St and reach Ruth Lyons Ln you've gone a little too far

    Then 0.05 miles
  13. Welcome to CINCINNATI, OH.

    1. Your destination is just past E Oneidia Aly

    2. If you reach W 9th St you've gone a little too far

    Then 0.00 miles