MapQuest Driving Directions Sikeston, MO to Memphis, TN

Sikeston, MO

Memphis, TN

Route 1

Go south on US-61 S.
141.111 miles
2hr 13min
  1. Start out going east on Tanner St toward Sikes Ave.

    Then 0.33 miles
  2. Turn right onto N Main St/US-61 S. Continue to follow US-61 S.

    1. US-61 S is just past Taylor St

    2. If you reach Heath St you've gone about 0.1 miles too far

    Then 17.13 miles
  3. Merge onto I-55 S toward Marston (Crossing into Arkansas).

    1. If you reach County Highway 728 you've gone about 1.5 miles too far

    Then 117.24 miles
  4. Keep left to take I-40 E/US-64 E toward Memphis/Nashville (Crossing into Tennessee).

    Then 5.35 miles
  5. Take the Front St N/Front St S/Riverside Dr exit, EXIT 1.

    Then 0.25 miles
  6. Keep left to take the Front St N/Front St S ramp.

    Then 0.13 miles
  7. Turn right onto N Front St.

    Then 0.51 miles
  8. Turn left onto Monroe Ave.

    1. Monroe Ave is just past Floyd Aly

    2. Allstate Insurance: Ezekeil Hudson is on the corner

    3. If you reach General Washburns Escape Aly you've gone a little too far

    Then 0.15 miles
  9. Turn right onto S 2nd St/TN-3/TN-14.

    1. S 2nd St is just past S November 6th St

    2. McEwen's Memphis is on the left

    3. If you reach Maggie H Isabel St you've gone a little too far

    Then 0.04 miles
  10. Welcome to MEMPHIS, TN.

    1. If you reach Union Ave you've gone a little too far

    Then 0.00 miles