MapQuest Driving Directions Tupelo, MS to Panama City, FL

Tupelo, MS

Panama City, FL

Route 1

Go east on US-78 E (Crossing into Alabama).
411.726 miles
7hr 3min
  1. Start out going east on E Main St/MS-178 toward S Front St.

    Then 1.16 miles
  2. Turn left onto N Veterans Blvd.

    1. N Veterans Blvd is 0.8 miles past E Franklin St

    2. If you reach Wayside St you've gone a little too far

    Then 1.88 miles
  3. Merge onto US-78 E (Crossing into Alabama).

    Then 114.77 miles
  4. Take the US-78 exit, EXIT 85, toward Adamsville/Birmingham.

    Then 0.32 miles
  5. Merge onto US-78 E/AL-4 toward Adamsville/Birmingham/Graysville.

    Then 11.98 miles
  6. Merge onto I-20 E/I-59 N toward Downtown.

    Then 1.39 miles
  7. Merge onto I-65 S via EXIT 124A toward Montgomery.

    Then 92.26 miles
  8. Take the US-80 E/US-82 E/South Boulevard exit, EXIT 168, toward US-31/US-231/US-331.

    Then 0.21 miles
  9. Turn left onto US-82 E/AL-21/AL-15/AL-6/W South Blvd.

    1. BEELINE STORE #207 is on the corner

    Then 5.31 miles
  10. Turn slight right onto Troy Hwy/US-82 E/US-231 S/AL-6/AL-53. Continue to follow US-231 S.

    1. US-231 S is just past Strathmore Dr

    Then 94.39 miles
  11. Turn right onto Ross Clark Cir/US-84 W/US-231 S/AL-210. Continue to follow Ross Clark Cir/US-231 S/AL-210.

    1. Ross Clark Cir is 0.1 miles past Buyers Dr

    Then 4.91 miles
  12. Turn right onto S Oates St/US-231 S/AL-1. Continue to follow US-231 S (Crossing into Florida).

    1. US-231 S is 0.8 miles past S Park Ave

    2. Mercedes-Benz Of Dothan is on the right

    Then 78.76 miles
  13. Turn slight right onto US-98 W/FL-30A/W 15th St. Continue to follow US-98 W.

    Then 4.40 miles
  14. Welcome to PANAMA CITY, FL.

    Then 0.00 miles