MapQuest Driving Directions Tupelo, MS to Chicago, IL

Tupelo, MS

Chicago, IL

Route 1

Go north on US-45 N.
640.1711 miles
10hr 4min
  1. Start out going east on E Main St/MS-178 toward S Front St.

    Then 0.62 miles
  2. Merge onto US-45 N via the ramp on the left toward Corinth.

    1. If you are on MS-6 and reach E Main St you've gone about 0.1 miles too far

    Then 1.43 miles
  3. Merge onto US-45 N toward US-78/Corinth.

    Then 1.58 miles
  4. Merge onto US-78 W toward Memphis (Crossing into Tennessee).

    Then 94.15 miles
  5. Merge onto I-240 W toward St Louis.

    Then 4.90 miles
  6. I-240 W becomes I-55 N (Crossing into Arkansas).

    Then 13.46 miles
  7. Keep right to take I-55 N via EXIT 277 toward Blytheville/Jonesboro (Crossing into Missouri).

    Then 130.91 miles
  8. Merge onto I-57 N via EXIT 66A toward Chicago (Crossing into Illinois).

    Then 118.03 miles
  9. Keep right to take I-57 N toward Chicago.

    Then 262.66 miles
  10. I-57 N becomes I-94 W.

    Then 11.60 miles
  11. Take the E Washington Blvd exit, EXIT 51C, toward 100 North.

    Then 0.16 miles
  12. Turn right onto W Washington Blvd.

    Then 0.05 miles
  13. W Washington Blvd becomes W Washington St.

    Then 0.16 miles
  14. Keep left at the fork to continue on W Washington St.

    Then 0.45 miles
  15. Welcome to CHICAGO, IL.

    1. Your destination is just past N Wells St

    2. If you reach N Clark St you've gone a little too far

    Then 0.00 miles