MapQuest Driving Directions Buffalo, NY to Lancaster, PA

Buffalo, NY

Lancaster, PA

Route 1

322.493 miles
5hr 39min
  1. Start out going south on S Elmwood Ave/NY-5 toward Jerge Dr.

    Then 0.23 miles
  2. Turn slight right toward I-190/I-90/Peace Br/Canada.

    Then 0.04 miles
  3. Turn slight right onto Church St.

    Then 0.09 miles
  4. Merge onto I-190 S/Niagara Trwy S toward I-90/Skyway.

    Then 5.15 miles
  5. Merge onto I-90 W/New York Trwy W via EXIT 53-61 toward Erie.

    Then 1.60 miles
  6. Merge onto NY-400 S/Aurora Expy S via EXIT 54 toward NY-16/West Seneca/East Aurora.

    Then 13.00 miles
  7. Take the US-20A/NY-78 exit toward East Aurora.

    Then 0.24 miles
  8. Keep left to take the ramp toward WARSAW.

    Then 0.05 miles
  9. Turn left onto Main St/US-20A E/NY-78. Continue to follow US-20A E.

    Then 35.20 miles
  10. Turn slight left onto US-20A E/NY-39/NY-20A/Leicester Rd. Continue to follow US-20A E/NY-39.

    1. If you are on Perry Rd and reach Jones Bridge Rd you've gone a little too far

    Then 2.43 miles
  11. Turn right onto NY-36/State Route 36. Continue to follow NY-36.

    1. NY-36 is 0.1 miles past York Rd

    2. If you reach Argenna Park you've gone about 0.1 miles too far

    Then 8.44 miles
  12. Merge onto I-390 S/Genesee Expy S toward Corning.

    Then 32.84 miles
  13. I-390 S/Genesee Expy S becomes I-86 E/NY-17 E/NY-15 S/Southern Tier Expy E.

    Then 23.06 miles
  14. Take the I-99 S exit, EXIT 44A, toward Williamsport.

    Then 0.88 miles
  15. Merge onto US-15 S (Crossing into Pennsylvania).

    Then 75.61 miles
  16. Merge onto US-15 S/Market St via EXIT 27A toward Lewisburg.

    Then 1.14 miles
  17. Turn slight left onto Montgomery Pike/US-15 S. Continue to follow US-15 S.

    1. US-15 S is just past E 7th Ave

    Then 34.84 miles
  18. Merge onto US-15 S/US-11 S toward Harrisburg.

    Then 32.97 miles
  19. Merge onto US-22 E/US-322 E toward Harrisburg.

    Then 13.06 miles
  20. Merge onto I-81 N/US-322 E toward I-83/Hershey/Hazleton.

    Then 2.78 miles
  21. Keep right to take US-322 E via EXIT 70 toward Pennsylvania Tpke/Hershey/York.

    Then 3.56 miles
  22. Take I-83 S toward Harrisburg/York/I-283 S/I-76/Pennsylvania Tpke/Airport/Lancaster.

    Then 0.76 miles
  23. Merge onto I-283 S via EXIT 46A on the left toward I-76/Pennsylvania Tpke/Airport.

    Then 2.86 miles
  24. Merge onto PA-283 E via EXIT 1A toward Airport/Lancaster.

    Then 28.73 miles
  25. Take the Fruitville Pike S exit toward Downtown Lancaster.

    Then 0.43 miles
  26. Merge onto Fruitville Pike.

    Then 0.92 miles
  27. Fruitville Pike becomes N Prince St.

    Then 1.33 miles
  28. Turn left onto W King St/PA-462.

    1. W King St is just past W Grant St

    2. Bee's Knees Bakery is on the right

    3. If you are on S Prince St and reach W Mifflin St you've gone a little too far

    Then 0.11 miles
  29. Take the 2nd left onto Penn Sq/PA-72. Continue to follow PA-72.

    1. PA-72 is just past N Market St

    2. Citizens Bank is on the corner

    3. If you are on E King St and reach S Christian St you've gone a little too far

    Then 0.11 miles
  30. Take the 1st left onto W Orange St/PA-462.

    1. W Orange St is just past E Grant St

    2. Stacked Carvery Restaurant & Catering is on the left

    3. If you reach E Chestnut St you've gone about 0.1 miles too far

    Then 0.06 miles
  31. Welcome to LANCASTER, PA.

    1. If you reach N Prince St you've gone a little too far

    Then 0.00 miles