MapQuest Driving Directions Altoona, PA to Greenville, SC

Altoona, PA

Greenville, SC

Route 1

Go southeast on 17th St.
577.035 miles
9hr 12min
  1. Start out going southeast on 12th St toward Green Ave.

    Then 0.11 miles
  2. Take the 2nd right onto 10th Ave.

    1. 10th Ave is just past 11th Ave

    Then 0.38 miles
  3. Turn slight right onto ramp.

    1. If you reach 19th St you've gone about 0.1 miles too far

    Then 0.09 miles
  4. Turn right onto 17th St.

    Then 1.66 miles
  5. Merge onto I-99 S/US-220 S toward Bedford.

    Then 32.59 miles
  6. Take EXIT 1 toward I-70/Pennsylvania Tpke/I-76/Pittsburgh/Harrisburg.

    Then 0.86 miles
  7. Merge onto Business 220/US-220 Bus S toward Bedford.

    Then 0.26 miles
  8. Merge onto I-70 E/I-76 E/Pennsylvania Tpke E toward Harrisburg (Portions toll).

    Then 16.09 miles
  9. Merge onto I-70 E via EXIT 161 toward US-30/Breezewood/Baltimore (Portions toll).

    Then 2.57 miles
  10. Take I-70 E toward Washington D.C/Baltimore (Crossing into Maryland).

    1. If you reach S Breezewood Rd you've gone about 0.1 miles too far

    Then 24.01 miles
  11. Merge onto US-522 S via EXIT 1B on the left toward Hancock/Winchester (Passing through West Virginia, then crossing into Virginia).

    Then 39.85 miles
  12. Merge onto VA-37 S toward US-50.

    Then 6.94 miles
  13. Merge onto I-81 S toward Roanoke.

    Then 228.66 miles
  14. Merge onto I-77 S via EXIT 81 toward Charlotte NC (Crossing into North Carolina).

    Then 117.98 miles
  15. Merge onto I-485 S via EXIT 19B toward Pineville/I-85 S.

    Then 11.45 miles
  16. Take EXIT 9-10 toward I-85/Spartanburg/US-29/US-74/Greensboro/Wilkinson Blvd.

    Then 0.45 miles
  17. Merge onto I-85 S via EXIT 10B toward Spartanburg/Gastonia (Crossing into South Carolina).

    Then 85.87 miles
  18. Take the I-385 exit, EXIT 51, toward Greenville/Columbia.

    Then 0.28 miles
  19. Merge onto I-385 N via EXIT 51C toward Greenville/Downtown.

    Then 6.00 miles
  20. I-385 N becomes E North St/SC-183.

    Then 0.32 miles
  21. Keep right at the fork to go on Beattie Pl/SC-183.

    Then 0.37 miles
  22. Take the 3rd left onto N Main St.

    1. N Main St is just past Insignia Pl

    2. Sushi Koji is on the corner

    3. If you are on College St and reach N Laurens St you've gone a little too far

    Then 0.24 miles
  23. Welcome to GREENVILLE, SC.

    1. Your destination is just past Piazza Plz

    2. If you are on S Main St and reach W McBee Ave you've gone a little too far

    Then 0.00 miles