MapQuest Driving Directions Roanoke, VA to Chicago, IL

Roanoke, VA

Chicago, IL

Route 1

Go north on I-581 N/US-220 N.
670.0442 miles
11hr 5min
  1. Start out going north on S Jefferson St toward Kirk Ave SE.

    Then 0.09 miles
  2. Take the 2nd right onto Campbell Ave SE/US-11 N.

    1. Campbell Ave SE is just past Kirk Ave SE

    2. City Corner Fresh Foods is on the corner

    3. If you reach Salem Ave SE you've gone a little too far

    Then 0.17 miles
  3. Turn left onto Williamson Rd SE/US-11 N/US-221 N.

    1. Williamson Rd SE is just past Market Sq SE

    2. Alejandro's Mexican Grill is on the right

    3. If you reach 3rd St SE you've gone a little too far

    Then 0.35 miles
  4. Merge onto I-581 N/US-220 N toward Lexington/Salem.

    Then 5.70 miles
  5. Merge onto I-81 S via EXIT 1S on the left toward Salem/Bristol.

    Then 25.06 miles
  6. Take the US-11/US-460 E/US-460 Bus exit, EXIT 118C, toward Christiansburg/Shawsville.

    Then 0.76 miles
  7. Merge onto Roanoke St/US-11 S/US-460 W toward Christiansburg/Virginia Tech.

    Then 0.90 miles
  8. Merge onto US-460 W toward Blacksburg (Crossing into West Virginia).

    Then 55.17 miles
  9. Merge onto I-77 N toward Beckley/TOLL ROAD (Portions toll).

    1. If you are on US Highway 460 and reach Service Rd you've gone about 0.3 miles too far

    Then 91.68 miles
  10. Keep left to take I-64 W via EXIT 101 toward Huntington.

    Then 17.90 miles
  11. Take the US-35 exit, EXIT 40, toward Winfield/Pt Pleasant.

    Then 0.41 miles
  12. Merge onto US-35 N toward Scott Depot (Crossing into Ohio).

    Then 97.63 miles
  13. Keep left to take US-35 W toward Dayton.

    Then 75.13 miles
  14. Take the Keowee St/Steve Whalen Blvd exit.

    Then 0.28 miles
  15. Keep left to take the Keowee St ramp toward Childrens Medical Center/Wayne Ave.

    Then 0.82 miles
  16. Keep right to take the ramp toward Fifth Third Field.

    Then 0.09 miles
  17. Merge onto S Keowee St.

    Then 1.25 miles
  18. Merge onto OH-4 S via the ramp on the left toward I-75/Toledo/Cincinnati.

    1. If you reach Earl Ave you've gone about 0.1 miles too far

    Then 0.27 miles
  19. Merge onto I-75 N toward Toledo.

    Then 6.07 miles
  20. Merge onto I-70 W via EXIT 61 toward Indianapolis (Crossing into Indiana).

    Then 100.90 miles
  21. Merge onto I-465 N/US-52 W via EXIT 90.

    Then 18.80 miles
  22. Keep left to take US-52 W via EXIT 25 toward I-65 N/Chicago.

    Then 17.22 miles
  23. Take I-65 N toward Chicago.

    Then 119.93 miles
  24. Take the I-90/Toll Road exit, EXIT 262, toward Illinois/Ohio.

    Then 0.59 miles
  25. Merge onto I-90 W toward Chicago (Portions toll) (Crossing into Illinois).

    Then 24.09 miles
  26. Merge onto I-94 W via the exit on the left.

    Then 7.98 miles
  27. Take the E Washington Blvd exit, EXIT 51C, toward 100 North.

    Then 0.16 miles
  28. Turn right onto W Washington Blvd.

    Then 0.05 miles
  29. W Washington Blvd becomes W Washington St.

    Then 0.16 miles
  30. Keep left at the fork to continue on W Washington St.

    Then 0.45 miles
  31. Welcome to CHICAGO, IL.

    1. Your destination is just past N Wells St

    2. If you reach N Clark St you've gone a little too far

    Then 0.00 miles