Mena is a city in Polk County, Arkansas, United States. It is also the county seat of Polk County. It was founded by Arthur Edward Stilwell during the building of the Kansas City, Pittsburg and Gulf Railroad (now the Kansas City Southern). It was Stilwell who decided Mena would be the name of this new town along the route to Port Arthur, Texas. He named her so in honor of his beloved friend and financier Jan DeGeoijen's wife, Folmina Margaretha Janssen DeGeoijen, whom Mr. DeGeoijen affectionately called Mena.
The population was 5,637 as of 2000 census.
Mena is located at 34°34′56″N 94°14′21″W / 34.58222°N 94.23917°W / 34.58222; -94.23917 (34.582208, -94.239039).