About This Place
De Soto is a village in Jackson County, Illinois, United States. The population was 1,653 at the 2000 census.
De Soto was largely destroyed by the Great Tri-State Tornado of 1925. Sixty-nine people died in De Soto when approximately 30% of the town was destroyed, and of this total 33 were children at a local school that collapsed from the winds. The tornado affected Missouri, Illinois, and Indiana killing 695 and injuring over 2,000.
De Soto is located at 37°48′56″N 89°13′41″W / 37.815660°N 89.228184°W / 37.815660; -89.228184.