Enterprise is a city in Dickinson County, Kansas, United States. As of the 2010 census, the city population was 855.
In 1887, Atchison, Topeka and Santa Fe Railway built a branch line from Neva (3 miles west of Strong City) through Enterprise to Superior, Nebraska. In 1996, the Atchison, Topeka and Santa Fe Railway merged with Burlington Northern Railroad and renamed to the current BNSF Railway. Most locals still refer to this railroad as the "Santa Fe".
Enterprise is located at 38°54′9″N 97°7′5″W / 38.9025°N 97.11806°W / 38.9025; -97.11806 (38.902485, -97.118172). According to the United States Census Bureau, the city has a total area of 0.7 square miles (1.7 km²), of which, 0.6 square miles (1.7 km²) of it is land and 1.49% is water.