Rothbury is a village in Grant Township, Oceana County in the U.S. state of Michigan. The population was 416 at the 2000 census.
According to the United States Census Bureau, the village has a total area of 1.0 square miles (2.6 km²), all land.
As of the census of 2000, there were 416 people, 157 households, and 118 families residing in the village. The population density was 420.8 per square mile (162.2/km²). There were 167 housing units at an average density of 168.9 per square mile (65.1/km²). The racial makeup of the village was 92.07% White, 1.92% Native American, 0.24% Asian, 5.05% from other races, and 0.72% from two or more races. Hispanic or Latino of any race were 9.13% of the population.