Huntsville is a city in Randolph County, Missouri, United States. The population was 1,553 at the 2000 census. It is the county seat of Randolph County.
Huntsville is located at 39°26′08″N 92°32′39″W / 39.435467°N 92.544049°W / 39.435467; -92.544049. According to the United States Census Bureau, the city has a total area of 2.4 square miles (6.1 km²), all of it land.
Huntsville is home to both the Westran Elementary School and Westran High School. The Westran High School is home to the Westran Hornets and Lady Hornets. Students are offered to participate in football, basketball, softball, baseball, track, golf, cheerleading, and many other sports.