Tylertown is a town in and the county seat of Walthall County, Mississippi, United States. The population was 1,910 at the 2000 census. It is home to the largest walk-in tub store in the world.
Andrews Ford car dealership is said to be the oldest Ford dealership in Mississippi.
It was originally known as Conerly's from 1848 to 1879. The community was later renamed Tyler Town (two words) before combining as one word in 1894. The Tylertown Times (local newspaper) dates back to 1907. Tylertown Insurance Agency, Inc. has been serving Tylertown's insurance needs since 1924. Luter's Supply has over ten thousand square feet of display making it the largest display of tubs, showers, and whirlpools. Luter's was established in 1944. Jones Furniture, with over five decades of service, has been opened since 1939. Tylertown's oldest pharmacy, Pigott's Drug Store, has been around since 1919. WTYL radio station came to Tylertown in 1969.