Bayboro is a town in Pamlico County, North Carolina, United States. The population was 741 at the 2000 census. It is the county seat of Pamlico County.
Bayboro is part of the New Bern, North Carolina Micropolitan Statistical Area.
Bayboro is located at 35°8′39″N 76°46′15″W / 35.14417°N 76.77083°W / 35.14417; -76.77083 (35.144229, -76.770751).