Karlsruhe (pronunciation: /kɑrlsruː/ karls-roo) is a city in McHenry County, North Dakota in the United States. The population was 82 at the 2010 census. It is part of the Minot Micropolitan Statistical Area. Karlsruhe was founded in 1912.
Karlsruhe is located at 48°5′27″N 100°37′15″W / 48.09083°N 100.62083°W / 48.09083; -100.62083 (48.090862, -100.620829).
According to the United States Census Bureau, the city has a total area of 0.8 square miles (2.0 km²), all of it land.