Harrison is a village in Sioux County, Nebraska, United States. The population was 279 at the 2000 census. It is the county seat of Sioux County.
Harrison is located at 42°41′17″N 103°52′56″W / 42.68806°N 103.88222°W / 42.68806; -103.88222 (42.687984, -103.882115).
According to the United States Census Bureau, the village has a total area of 0.3 square miles (0.8 km²), all of it land.