Lyons is a city in Burt County, Nebraska, United States. The population was 851 in the 2010 U.S. Census. The city is named after its founder.
Waldo Lyon purchased the land and erected the first building in the community in 1868. After the arrival of the railroad in 1881, prosperity seemed assured and incorporation followed in 1884. Much of the community, including Main Street, is constructed of brick due to the large amount of clay found locally.
The founder was against the consumption of alcoholic beverages, and prohibition remained in force until overcome by a public referendum in 1974.