Pelion is a town in Lexington County, South Carolina, United States. The population was 553 at the 2000 census. It is part of the Columbia, South Carolina Metropolitan Statistical Area. The town was named after Mt Pelion in Greece.
Pelion is located at 33°45′56″N 81°14′47″W / 33.76556°N 81.24639°W / 33.76556; -81.24639 (33.765562, -81.246472).
According to the United States Census Bureau, the town has a total area of 3.6 square miles (9.2 km²), of which, 3.5 square miles (9.0 km²) of it is land and 0.1 square miles (0.3 km²) of it (2.81%) is water.