Charleston is a city in Bradley County, Tennessee, United States. The population was 651 at the 2010 census. It is included in the Cleveland, Tennessee Metropolitan Statistical Area.
Charleston is situated along the south bank of the Hiwassee River, which flows down out of the Appalachian Mountains several miles to the east and empties into the Chickamauga Lake impoundment of the Tennessee River several miles to the west. The river forms the boundary between Bradley County and McMinn County. Calhoun, Charleston's sister city, is situated on the north bank of the Hiwassee, on the McMinn County side.
Charleston is traversed by U.S. Route 11, which enters the city from Calhoun to the north and exits the city en route to Cleveland to the south. Interstate 75, which roughly parallels US-11 in the area, runs along Charleston's western boundary.