Mobeetie is a city in northwestern Wheeler County, Texas, United States, just across the Sweetwater Creek from Texas Route 152. The population was 107 at the 2000 census.
A trading post for hunters and trappers for nearby Fort Elliot (aka "Cantonment Sweetwater"), the settlement was first a buffalo hunter's camp unofficially called "Hidetown." The first formal name for the town was "Sweetwater." On January 24, 1876, occurred the "Sweetwater Shootout," Anthony Cook (aka Corporal "Sergeant" Melvin A. King; of the then 4th Cavalry-Company H, stationed at Fort Elliot), shot and killed Mollie Brennan (a dance hall girl and former prostitute). Sgt. King then wounded Bat Masterson, who in return killed him (King may have shot Masterson first and then killed Brennan, accounts vary). Texas cattleman Charles Goodnight said about the town: "I think it was the hardest place I ever saw on the frontier except Cheyenne, Wyoming."
When the town applied for a post office in 1879, the name "Sweetwater" was already in use. The town took the new name of "mobeetie," believed to be a Native American word for "Sweetwater." Later it was discovered that the word actually means "buffalo feces".