Gainesville is a census-designated place (CDP) in Prince William County, Virginia, United States. The population was 33,182 in the 2010 census.
Gainesville was once a changing point for stagecoach horses on the Fauquier & Alexandria Turnpike. In 1852, the Manassas Gap Railroad reached the area and the stop became known as Gainesville. The town was a shipping point for grain, timber, and cattle and remained a major cattle shipping point into the early 1960s. During the American Civil War, nearby Thoroughfare Gap in the Bull Run Mountains served as a path for soldiers to reach the First and Second battles of Bull Run. In 1994, the groundbreaking for the town's first townhome community began; it was named Crossroads. This marked the beginning of mass-development for Gainesville.
In 2006, VDOT began working on the Gainesville Interchange improvement project in order to ease the traffic in the rapidly growing Gainesville-Haymarket area.