Huntington is a city in Cabell and Wayne counties in the U.S. state of West Virginia, along the Ohio River. Most of the city is in Cabell County, for which it is the county seat. A small portion of the city, mainly the neighborhood of Westmoreland, is in Wayne County. Its population was 49,138 at the 2010 census. Huntington is a part of the Huntington-Ashland, WV-KY-OH, Metropolitan Statistical Area (MSA). As of 2009, the MSA's population was 285,624. Huntington is the largest city within the MSA and the second largest city in West Virginia, behind Charleston. The city is also the home of Marshall University.
The city was named for Collis P. Huntington, who founded Huntington in 1870 as the western terminus for the Chesapeake and Ohio Railway (C&O) on the land west of the mouth of the Guyandotte River at the Ohio River. It was created as a railroad town for the C&O, when it initially stretched from Richmond, Virginia to the Ohio River. The city houses numerous railroad shops which expanded east to Newport News (and coal piers) and west to eventually reach Cincinnati and Chicago in the years after its founding.
The first permanent settlement in what is now modern-day Huntington was founded in 1775 as "Holderby's Landing."