Hydaburg ( /haɪdəbɜrɡ/) is a town in the Prince of Wales-Hyder Census Area, in the U.S. state of Alaska. The population was 382 at the 2000 census.
Hydaburg is located at 55°12′17″N 132°49′15″W / 55.20472°N 132.82083°W / 55.20472; -132.82083 (55.204699, -132.820859). It is the southernmost city on Prince of Wales Island. Hydaburg is located on the north shore of Sukkwan Strait, which connects to Cordova Bay through Hetta Inlet.
According to the United States Census Bureau, the city has a total area of 0.3 square miles (0.8 km²), all of it land.