Hoxie is a city in Lawrence County, Arkansas, United States. The population was 2,817 at the 2000 census. Hoxie lies immediately south of Walnut Ridge.
Hoxie is located at 36°2′55″N 90°58′38″W / 36.04861°N 90.97722°W / 36.04861; -90.97722 (36.048616, -90.977296).
According to the United States Census Bureau, the city has a total area of 4.0 square miles (10.3 km²), all of it land.