Jonesboro is a city in and one of the two county seats of Craighead County, Arkansas, United States. According to the 2010 US Census, the population of the city was 67,263. A college town, Jonesboro is the largest city in northeastern Arkansas and the fifth most populous city in the state. It is the principal city of and is included in the Jonesboro, Arkansas Metropolitan Statistical Area. In 2010, the Jonesboro metropolitan area had a population of 121,026 and an estimated population (2009) of 161,135 in the Jonesboro-Paragould Combined Statistical Area.
Jonesboro is home to Arkansas State University and is a regional center for manufacturing, agriculture, medicine, education, and trade.
The Jonesboro area was first inhabited by Indian tribes which included the Osage, the Caddo, and the Quapaw. The name of the state of Arkansas actually comes from the Quapaw language. American settlers eventually made their way to the area where Jonesboro is located and began exploring, hunting, trapping, and trading with the local Indian tribes. A permanent settlement of Jonesboro was set up shortly after 1815.