Sacramento is the capital city of the U.S. state of California and the county seat of Sacramento County. It is located at the confluence of the Sacramento River and the American River in the northern portion of California's expansive Central Valley. With a population of 486,488 at the 2010 census, it is the sixth-largest city in California. Sacramento is the core cultural and economic center of the Sacramento metropolitan area which includes seven counties; with an estimated population of 2,527,123. Its metropolitan area is the fourth largest in California after the Greater Los Angeles Area, San Francisco Bay Area, and the San Diego metropolitan area as well as the 22nd largest in the United States. A city attaining global status, Sacramento was cited by Time magazine as America's most ethnically and racially integrated city in 2002.
Sacramento became a city through the efforts of the Swiss immigrant John Sutter, Sr., his son John Sutter, Jr., and James W. Marshall. Sacramento grew quickly thanks to the protection of Sutter's Fort, which was established by Sutter in 1839. During the California Gold Rush, Sacramento was a major distribution point, a commercial and agricultural center, and a terminus for wagon trains, stagecoaches, riverboats, the telegraph, the Pony Express, and the First Transcontinental Railroad.
California State University, Sacramento, more commonly known as Sacramento State or Sac State, is the major local university. It is one of the twenty-three campuses of the California State University system. In addition, the University of California, Davis, is located in nearby Davis, 15 miles (24 km) west of the capital. The UC Davis Medical Center, a world-renowned research hospital, is located in the city of Sacramento.