Physicist Shiu-Shin Chio, Ph.D., founded Pulse Metric in 1990. His founding vision was to apply principles of biophysics and computer technologies to the development of advanced non-invasive tools that will help clinicians better detect and treat hypertension, heart failure and associated cardiovascular disease. The company's DynaPulse line of non-invasive hemodynamic monitors, when coupled to the DynaPulse Analysis Center Web site, provide clinicians the capability to measure hemodynamic values at the same time they record a patient's blood pressure using an upper-arm cuff. Within a minute of a physician's uploading a patient's blood pressure measurement, Pulse Metric's patented analysis technologies produce a 16-point hemodynamic profile, including values for cardiac output, vessel compliance/distensibility, left ventricular contractility and systemic vascular resistance. Pulse Metric is located in San Diego.