Palisade is a Statutory Town in Mesa County, Colorado, United States. It is part of the Grand Junction Metropolitan Statistical Area. The population was 2,579 at the 2000 census.
Palisade is known for its peach orchards, wine vineyards, and is considered Colorado's peach capital.
Palisade is located at 39°6′34″N 108°21′15″W / 39.10944°N 108.35417°W / 39.10944; -108.35417 (39.109335, -108.354277).