Casa Santo Stefano

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1607 N 22nd St
Tampa, FL 33605
Open for lunch, dinner, curbside takeout and rooftop Santo's Drinkeria. Housed in a former 1925 Ybor City macaroni factory, Casa Santo Stefano pays tribute to the Sicilian food owner Richard Gonzmart ate every Sunday with his best friend Vincent Palori. Those Nana-cooked meals inspire the pastas, sauces and seafood we feature here, not just Sicilian, but Tampa Sicilian. The Casa interior design offers a showplace of art and craftsmanship, with custom imported elements around every corner. Casa also pays tribute to the wave of Sicilian immigrants who -- along with the Cubans and Spanish -- helped build Tampa and Ybor City after coming to America looking for a better life. Specifically, 60 percent of the Sicilians in Tampa came from Santo Stefano Quisquina and Alessandria della Rocca. This restaurant tells their history. Begun in friendship, nurtured by family and continued in community, Casa Santo Stefano offers a look back to Sunday suppers, simpler times and shared stories.

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Reviews

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4.5640 reviews
Photo of Addessa J.
Addessa J.
12/30/2025

My friend and I came here for desserts The lemon vanilla cake is my favorite and my friend enjoyed hers as well. We were given a very nice slice for each of us . I also had a cappuccino with my...

Photo of Amber N.
Amber N.
11/7/2025

It had a comfortable atmosphere and friendly service. Overall the experience was good-- some things could be better; others were great. Grapefruit basil smash mocktail (2/5) -- It was good at...

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Zeena A.
11/1/2025

I came here for an early lunch and let me start by saying the inside is beautiful! They have a rooftop on the second floor with a bar and cigar lounge, which is definitely a nice touch. There is a...

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Jen C.
1/2/2026

Classic Italian restaurant. The interior is decorated with lovely old photos. Had the best service I've experienced in a long time dining here. The waiter was professional, knowledgeable about the...

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Olesya P.
10/19/2025

Came here for a brunch. We made a reservation a few days ahead. Service was absolutely exceptional! It's very hard to find a place with truly amazing server. Vince was above and beyond! Ambience...

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