Manchester is a city located in Meriwether and Talbot Counties in the U.S. state of Georgia, although primarily in Meriwether. The population was 3,988 at the 2000 census.
As of the census of 2000, there were 3,988 people, 1,629 households, and 1,057 families residing in the city. The population density was 698.1 people per square mile (269.7/km²). There were 1,853 housing units at an average density of 324.4 per square mile (125.3/km²). The racial makeup of the city was 56.22% White, 42.23% African American, 0.33% Native American, 0.65% Asian, 0.10% from other races, and 0.48% from two or more races. Hispanic or Latino of any race were 0.70% of the population.
There were 1,629 households out of which 28.7% had children under the age of 18 living with them, 39.5% were married couples living together, 21.4% had a female householder with no husband present, and 35.1% were non-families. 31.4% of all households were made up of individuals and 14.5% had someone living alone who was 65 years of age or older. The average household size was 2.45 and the average family size was 3.09.