Exira is a city in Audubon County, Iowa, United States, along the East Nishnabotna River and U.S. Route 71. The population was 810 at the 2000 census.
The oldest town in Audubon County, Exira was founded in 1857. The town was named for Exira Eckman, daughter of Judge John Eckman from Ohio, who agreed to purchase a lot of property in the town if the town was named for his daughter.
The main industries in and around Exira are agriculture and agribusiness. Exira has an elementary school, built in 1913, and a high school, completed in 1959. There are four churches in the town.