Clinton is the largest city in DeWitt County, Illinois, United States. The population was 7,225 at the 2010 census. It is the county seat of DeWitt County.
The city and the county are named for DeWitt Clinton, governor of New York, 1817-1823. Clinton Nuclear Generating Station is located 6 miles away on Clinton Lake.
Clinton is centrally located in the heart of Illinois, at 40°9′8″N 88°57′33″W / 40.15222°N 88.95917°W / 40.15222; -88.95917 (40.152240, -88.959214), accessible from Routes 51, 54, and 10.