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Keenes is a village in Wayne County, Illinois, United States. The population was 99 at the 2000 census.
Keenes is located at 38°20′15″N 88°38′29″W / 38.3375°N 88.64139°W / 38.3375; -88.64139 (38.337483, -88.641331).
According to the United States Census Bureau, the village has a total area of 0.1 square miles (0.3 km²), all of it land.