Oral-B Laboratories manufactures Oral-B brands that have helped Gillette become a worldwide leader in both the manual and power toothbrush markets. The Oral-B brand is a leader in the $4.5-billion toothbrush category, marketing toothbrushes for children and adults, as well as a variety of interdental products, such as dental floss. The Oral-B brand includes power toothbrushes for adults and children, as well as interdental products, such as irrigators and oral care centers. Oral-B toothbrushes, the foundation and largest category of Gillette's thriving oral care business, are used by more dentists and consumers than any other brand in the United States and in many international markets. Gillette, headquartered in Boston, is one of the world leaders in male grooming, a category that includes blades, razors and shaving preparations. Gillette also holds a top position worldwide in selected female grooming products, such as wet shaving and hair epilation devices. Oral-B Laboratories maintains a location in Iowa City, Iowa.