Pacific Institute for Research and Evaluation ( PIRE ) is one of the nation's preeminent independent, nonprofit organizations focusing on individual and social problems associated with the use of alcohol and other drugs. PIRE is dedicated to merging scientific knowledge and proven practice to create solutions that improve the health, safety, and well-being of individuals, communities, nations and the world. The Institute has a significant national presence in the area of prevention, with funded research projects at its ten research centers located around the country.PIRE scientists and practitioners continually focus on the design and implementation of complex program evaluation strategies and the conduct of research related to health and social issues, including criminal justice. PIRE provides training and technical assistance in many health-related areas to states and communities that are attempting to mitigate the effects of alcohol and other drug abuse.In all its work, PIRE maintains a commitment to the application of research findings in solution of real-world problems, achieved, in part, by translating scientific knowledge into practical guidance for policymakers and practitioners.PIRE is a California-chartered, not-for-profit corporation, that qualifies for tax-exempt status under section 501 ( c ) the IRS code. Annual form 990s are available on this website.