Cherokee is a city in Crawford County, Kansas, United States. As of the 2010 census, the city population was 714.
According to the United States Census Bureau, Cherokee has a total area of 0.7 square miles (1.8 km²), all of it land.
As of the census of 2000, there were 722 people, 301 households, and 192 families residing in the city. The population density was 1,052.2 people per square mile (404.0/km²). There were 336 housing units at an average density of 489.7 per square mile (188.0/km²). The racial makeup of the city was 95.43% White, 0.28% African American, 0.97% Native American, 0.14% Asian, and 3.19% from two or more races. Hispanic or Latino of any race were 0.42% of the population.