Ozawkie is a city in Jefferson County, Kansas, United States. It is part of the Topeka, Kansas Metropolitan Statistical Area. The population was 552 at the 2000 census. Located adjacent to Perry Lake, Ozawkie formerly existed in a different location but was relocated prior to the reservoir's construction.
According to the United States Census Bureau, the city has a total area of 0.3 square miles (1 km²), all of it land.