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Wetmore is a city in Nemaha County, Kansas, United States. As of the 2010 census, the city population was 368.
Wetmore is located at 39°38′4″N 95°48′34″W / 39.63444°N 95.80944°W / 39.63444; -95.80944 (39.634522, -95.809462). According to the United States Census Bureau, the city has a total area of 0.4 square miles (1.0 km²), all of it land.
As of the census of 2000, there were 362 people, 139 households, and 97 families residing in the city. The population density was 943.6 people per square mile (367.8/km²). There were 156 housing units at an average density of 406.6 per square mile (158.5/km²). The racial makeup of the city was 98.90% White, 0.55% Native American, and 0.55% from two or more races. Hispanic or Latino of any race were 0.28% of the population.