Shepherdsville is a city in Bullitt County, Kentucky, United States, just south of Louisville. The population was 8,334 at the 2000 census, but 2009 estimates put the city at 9,344. It is the county seat of Bullitt County.
Shepherdsville was founded by and named after Adam Shepherd in 1793. In its early days, the major industry in Shepherdsville was salt production from nearby Bullitt's Lick. The first post office in Shepherdsville opened in 1806. In 1836, a mineral water spa called Paroquet Springs opened. The mineral water supposedly had medicinal properties and so sufferers from a variety of maladies would visit Shepherdsville to drink and bathe in the water. During the American Civil War, the railroad bridge over the Salt River at Shepherdsville was a potential target for sabotage and was guarded by Union troops. In 1879, the Paroquet Springs hotel burned to the ground, but water from the springs continued to be bottled and sold until 1915. Throughout most of the 20th century, Shepherdsville was primarily an agricultural area. With the construction of the Kentucky Turnpike in the 1950s and Interstate 65 in the 1980s, people who worked in Louisville, Kentucky could live outside the city. From then on Shepherdsville experienced a period of rapid growth.
The deadliest train wreck in Kentucky history, which killed about fifty people in a two-train collision, took place in Shepherdsville several days before Christmas in 1917.