Simsboro is a village in western Lincoln Parish, Louisiana, United States. The population was 684 at the 2000 census. It is part of the Ruston Micropolitan Statistical Area.
Simsboro is located at 32°32′3″N 92°47′11″W / 32.53417°N 92.78639°W / 32.53417; -92.78639 (32.534169, -92.786417).
According to the United States Census Bureau, the village has a total area of 3.5 square miles (9.0 km²), all land.