Brandywine is an unincorporated area and census-designated place (CDP) in Prince George's County, Maryland, United States, although the postal delivery area includes part of Charles County as well near Malcolm.
The population of Brandywine (CDP) was 1,410 at the 2000 census, which is a small percentage of the area covered by the Brandywine post office. The Brandywine zip code covers a very large area both east and west of busy Maryland Route 5/U.S. Route 301, which merge at Brandywine. Cedarville State Forest and the picturesque Baden community to the east, including a trailer park community, are part of greater Brandywine. The Census also refers to "District 11, Brandywine, Maryland" which had a population of 12,313 in 2000 and an estimated 15,877 in 2009.
Although surrounded on either side by the sizable communities of Clinton and Waldorf, Brandywine itself has remained primarily rural and scenic; however, this is beginning to change, with new housing developments being built. The first phase of Brandywine Crossing shopping center opened in October 2008. The community also includes Gwynn Park High School, a golf course, and a construction equipment sales lot.