Sharptown is a town in Wicomico County, Maryland, United States. The population was 649 at the 2000 census. It is included in the Salisbury, Maryland Metropolitan Statistical Area.
Sharptown is located at 38°32′26″N 75°43′8″W / 38.54056°N 75.71889°W / 38.54056; -75.71889 (38.540630, -75.719021).
According to the United States Census Bureau, the town has a total area of 0.5 square miles (1.2 km²), of which, 0.4 square miles (1.1 km²) of it is land and 0.04 square miles (0.1 km²) of it (8.70%) is water.